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Side effects drop significantly at lower doses, and costs can be one-quarter to one-third of standard therapy

N Engl J Med 389(12):10691084 Kosiborod MN, Petrie MC, Borlaug BA, Javed B, Davies MJ, Hovingh GK et al (2024) Semaglutide in patients with obesity-related heart failure and type 2 diabetes

The MHRA does permit the use of unlicensed medicines in specific, tightly controlled circumstances for example, under a 'Specials' licence (as set out in MHRA guidance on the supply of unlicensed medicinal products) or within an authorised clinical trial but this does not extend to prescribing experimental compounds for bodybuilding or aesthetic purposes

Ribeiro et al

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Since tirzepatide already reduces appetite, most users naturally eat less at each sitting